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Medical Technologies Innovation Hub

Dissemination-SMES Engagement

Characterization

Preclinical Research

Test Cases Developers

Technology Assessment

Manufacturing

Clinical Research

Coordination & Technical Management

Regulatory & HTA

Copyright 2023 Safe-n-Medtech. All rights reserved.

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communication@cebr.net

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This project has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under Grant Agreement No 814607

San Vicente de Barakaldo,
País Vasco / Euskadi (Spain)

+34 622 000 000

angel.delpozo@keralty.com

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This project has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under Grant Agreement No 814607

The Institute of Physical Chemistry ‘Ilie Murgulescu’ of the Romanian Academy

Role: Characterization

Contact: Speranta Tanasescu

Short Presentation:

The Institute of Physical Chemistry “Ilie Murgulescu” of the Romanian Academy (www.icf.ro) was founded in 1963 by Academician Ilie Murgulescu who is also the founder of the modern school of physical chemistry at the University of Bucharest. At present, IPC stands as a unit of complex research that may approach a wide spectrum of basic and advanced problems of physical chemistry including quantum chemistry and molecular structure, chemical thermodynamics, chemical kinetics, surface chemistry and catalysis, electrochemistry and corrosion, oxide compounds and materials science, colloidal chemistry and coordination chemistry. The research activity in IPC is developed over ten programs, undertaken in 8 laboratories (one for each research area presented above) and 2 working groups for surface, interface and thin film analysis by X-ray photoelectron spectroscopy (XPS), and for high performance computing in materials science.

The research group involved in the project comes from The Laboratory of Chemical Thermodynamics which is a leading laboratory for basic and applied thermodynamic research, the scientific team leader being Dr. Speranta Tanasescu. She is Senior Researcher I and Ph.D. Supervisor. The research team is composed of three senior scientists and eight junior scientists. The members of the research group have an extensive experience in the research work of physical chemistry and related interdisciplinary fields. They are drawn from chemistry, biochemistry, materials and engineering backgrounds; especially the senior researchers have significant cross-disciplinary practice. Also there is a good experience of successful prior cooperation within the international (HORIZON2020, FP7, FP6, COST, SCOPES, DOE, POS-CCE), national R&D programs (Partnership-Program, CEEX, CNCSIS, Romanian Academy Grants etc.), bilateral and inter-academic cooperation. The research results have been published in important international refereed journals, books and have been communicated at different scientific national and international conferences. The original thermodynamic data were included in the Gmelin Handbuch der Anorganischen Chemie, „NIST”-Thermodynamic database, in the network of “Center for Rare Earth and Magnetics/Rare-earth Information Center” (CREM/RIC), “Bibliography on Thermodynamic Properties of Materials at High Temperatures”, “Rare-Earths” Japanese Journal, International Data Series-Selected Data, International Electronic Journal of Phys-Chem Data and were cited in PhD Theses and scientific papers.

Main areas of interest in the Laboratory of Chemical Thermodynamics:

(A). Nanosciences, Nanotechnologies, Materials and new Production Technologies

A careful evaluation of the trade-off between structure, the grain size (method of preparation), thermodynamic stability
The understanding of the property dependence on compositional variables: the key to enable optimization and full exploitation of multifunctional materials
The control of the energetic parameters: important step in understanding the stability, possibilities to interaction with the biologic systems and the environmental effects of/on nanoparticles.

(B). Life sciences and biotechnology

Thermodynamic and thermochemical study of biological interest compounds (amino acids, peptides, proteins, enzymes etc) as basical compounds and models for a better understanding of living organisms
Thermodynamic characterization of the biomolecules–nanoparticle binding interaction
Thermodynamics of binding interactions at various stages in the rational drug design process. Targeted applications: Therapeutic NPs, Nanocarriers & Transporter molecules/particles

University of Liverpool

Role: Technology assessment

Contact: Marco Siccardi (Senior Lecturer)

Short Presentation:

At the core of our lab stands the mechanistic understanding of drug/therapeutics distribution in the human body with the overall objective of providing solutions for the current obstacles hindering effective theapies. Our research group focuses on multiple experimental and computational approaches with projects spanning from the identification of patient characteristics influencing drug efficacy and toxicity, management of complex clinical scenarios and enhancement of drug delivery through innovative advanced materials.

Based at the University of Liverpool our team consists of post-doctoral researchers, PhD and masters students with a range of backgrounds in pharmacology, chemistry, molecular and cellular biology. With collaborations on a national and international level with both academia and industry, we pride ourselves on the quality and diversity of our work and are continuously looking to develop new relationships.

University of Liverpool: The University of Liverpool has, since 1881, worked for the advancement of learning and ennoblement of life. This remains our mission today and will give focus to all our efforts in the coming years as we strive to achieve our ambitions and aspirations, tackle the grand challenges of the age and make our vision a reality. We have laid down this explicit challenge of where we want to be in 10 years’ time, and now we must be just as clear on how we will get there.

We start from a position of strength. As a connected, global University with multiple physical and virtual campuses – Liverpool, London, Suzhou, Singapore and online – our worldwide influence and impact is unrivalled in higher education. Over the next decade we will build on our internationally recognised strengths in research and scholarship and increase collaborative and inter-disciplinary working. We will continue to develop a high-quality environment in which to educate well-rounded, enquiring global citizens who connect and engage – through their learning, research, civic engagement and inter-cultural understanding – with the world’s most pressing problems. We will integrate teaching and research to ensure that we derive the maximum benefit from our rich environment of intellectual enquiry and challenge.

The University values diversity; we are an inclusive institution, committed to the provision of opportunity for those with the capacity to benefit as individuals but also as members of a wider community dedicated to a sustainable and just society. We will be guided by strong ethical principles and ensure that our values are embedded in our plans and actions.

We will commit to a culture of continuous improvement and collaborative working, ensuring that we encourage and value the contributions of staff and students to decision-making, and foster good governance through a culture of openness and transparency. We respect difference, but will look for consistency and sharing of good practice to ensure that fairness and equality of opportunity inform our organisational structures and processes.

We will be confident and ambitious as we face future challenges, nurturing all our staff and supporting their personal and professional development in an environment of constant change. We will acknowledge and reward contributions to the achievement of the highest possible standards in every aspect of our work.

Our educational offer and world-leading research will be recognised regionally, nationally and internationally as distinctively collaborative. We place the utmost value on partnership working and we will continue to shape a robust network of education and industry alliances, forging productive relationships worldwide, building capacity and advancing knowledge.

+34 622 000 000

angel.delpozo@keralty.com

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Meet the Consortium!

Partners

Copyright 2023 Safe-n-Medtech. All rights reserved.

CONTACT

communication@cebr.net

Síguenos en

San Vicente de Barakaldo, País Vasco / Euskadi (Spain)

+34 622 000 000

angel.delpozo@keralty.com

Síguenos en

CEBR

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INL

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Instituto de Medicina Molecular João Lobo Antunes

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BioKeralty

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Tecnalia

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Centre Interdisciplinaire de Nanoscience de Marseille

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China pharmaceutical University

Sintef Industry

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The Institute of Physical Chemistry ‘Ilie Murgulescu’ of the Romanian Academy

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Trinity College Dublin

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University of Pavia

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CIBER-bbn

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National Center for Nanoscience and Technology (NCNST)

STAMI

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VITO

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Eindhoven University of Technology

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Resonant Circuits Limited

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Stryker

Tecnan

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EuroScan International Network e.V.

Greendecision Srl

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University of Liverpool

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Hubei Gedian Humanwell Pharmaceutical Co.

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Organización Sanitas Internacional - Keralty

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Vall d'Hebron Research Institute

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MARACA International

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Osteba

San Vicente de Barakaldo,
País Vasco / Euskadi (Spain)